Everything about megatomi.com
Everything about megatomi.com
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Our new Crystal clear+ tissue clearing system is the only approach that delipidates samples without transform in morphology and with negligible influence on structural integrity.
Megatome is really a vibrating microtome created to area a wide range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome allows large-throughput tissue sectioning with uniform floor profile, together with negligible tissue destruction and information loss.
Antibodies might consider weeks to diffuse via only a few millimeters of tissue, having a steep labeling gradient from surface to core.
Megatome is designed for accuracy: the blade vibrates at a higher frequency and larger amplitude range than other microtomes, and features a distinctive deflection Handle system.
SE works by using a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) all through a porous sample with out damaging electrically billed buildings in the tissue. This enables two-four day clearing of intact organs,
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Megatome is a novel microtome which allows for prime-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue harm and knowledge reduction.
eFLASH is a quick tissue labeling approach that enables for uniform full-organ staining in twenty rounds of labeling.
The SmartSPIM mild sheet microscope presents unparalleled resolution and acquisition pace all over intact tissue volumes, although its modular design lets you upgrade and personalize individual elements.
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Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, safeguarding specimens for various rounds of processing.
Leverage the Obvious+ tissue clearing system, along with eFLASH and patented stochastic electrotransport technologies, to swiftly crystal clear and label full organs. Key highlights and attributes contain:
Our novel Protect tissue preservation procedure forms intramolecular bonds utilizing polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.